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Examination of congenital predispositions to blood clots (thrombophilic mutations)
Increased blood coagulation is influenced by congenital dispositions and external factors (physical activity, smoking, obesity, hormonal contraception, etc.) Individuals with increased blood clotting are at risk of blood clots; blood clots can close blood vessels, cause pulmonary embolism. Blood clots can form in the placenta during pregnancy and jeopardise the course of pregnancy.
We are investigating two significant changes:
Leiden mutation (FV Leiden)
Mutation of the coagulation factor II gene (FII prothrombin)
A significant mutation indicates an innate predisposition to increased blood clotting. If thrombophilic mutations are found, precautionary measures should be taken.